Request for Proposals
Letter of Intent Due March 19th
Those invited to apply for funding will be informed by March 22, 2018
Applications due April 16th at 5:00pm EST
The NIAMS-funded Center for Skeletal Research (CSR), based in the Endocrine Unit at MGH, is announcing a request for Pilot and Feasibility Research proposals. . The CSR’s goal is to enrich the research experience of skeletal biology researchers in New England. TWO grant ($30,000/year) will be awarded this year., NO RENEWALS ARE ALLOWED. Awardees will be expected to present progress to CSR members biannually and provide a written annual report.
Eligibility is based on the criteria listed below:
- Junior faculty proposing highly focused Skeletal Biology research projects with the goal of generating preliminary data sufficient to support an application for independent NIH research support. Applicants in this group must meet the NIH Early Investigator Criteria (New Investigators who have had less than 10 years of research or research training experience after the completion of their terminal research degree or medical residency, see http://grants.nih.gov/grants/new_investigators/index.htm). Awardees of K grants in their last 2 years of K funding may apply with committed effort but cannot receive salary from the P&F.
- Established researchers from outside the bone field proposing innovative studies relevant to Skeletal Biology.
- Established Skeletal Biology investigators proposing studies relevant to Skeletal Biology that represents a clear departure from their established line of investigation.
- IACUC/IRB approval must be received prior to funding.
Investigators must invest at least 1 calendar month of effort. If salary requests do not reflect this effort, cost-sharing plans must be indicated. Applicants who are not U.S. citizens or permanent U.S. residents must have active visas permitting them to remain in the U.S. for the full period of the proposed research.
Funding is anticipated to start on or before June 1, 2018.
- Applicants should send a Letter of intent to firstname.lastname@example.org on or before Monday, March 19 in the following format:
– a 250 word abstract
– a 150 word statement of eligibility
– an NIH style biosketch including all other support.
- Those invited to apply for funding will be informed by March 22, 2018
Please submit the following in single PDF file via email to email@example.com by Monday, April 16th
In the subject line include your last name and “P30P+FSpring2018” eg: TurnerP30P+FSpring2018
- PHS Form 398 pages 1,2,4 and 5 including a budget justification, Checklist page. The CSR will fund two grants up to $30,000 in direct costs for a one year period, June 1, 2018 -May 31, 2019.
- Research plan, including Specific Aims on PHS 398 continuation page, not to exceed 3 pages conforming to standard NIH font and margin requirements. Page limitations exclude references.
- NIH Biosketch format including other support with dollar amounts.
- A personal statement describing the candidate’s background and addressing eligibility criteria above (category 1,2 or 3), current goals and how the P&F will impact these goals, not to exceed 500 words.
Support from the CSR must be acknowledged on all resulting manuscripts.
|PI||Title of Project|
|Diana L. Carlone, Ph.D.||Cfp1 Action in Chondrogenesis|
|LI Zeng, Ph.D.||The Role of T lymphocytes in Osteoarthritis Progression|
|Frank Ko, Ph.D.||The effects of caloric restriction on bone formation and mTOR signaling|
|Michaela Reagan, Ph.D.||Targeting sclerostin in multiple myeloma-induced bone disease|
|Keertik Fulzele, Ph.D.||Metabolic effect of bone secreted Wnt-signaling inhibitor sclerostin|
|Marc Wein, M.D., Ph.D.||Control of osteocyte biology by salt inducible kinases|
|(Year 2) Agnes Berendsen, Ph.D.||VEGF-dependent control of osteoblast/adipocyte differentiation|
|Jenna Galloway, Ph.D.||A zebrafish model of tendon-bone attachment injury and regeneration|
|Agnes Berendsen, Ph.D.||VEGF-dependent control of osteoblast/adipocyte differentiation|
|Melissa Putman, M.D.||Whole body vibration to prevent the musculoskeletal complications of immobility|