Two post-doctoral associate positions available at Bais Lab related to 1) cartilage regeneration and osteoarthritis 2) cancer basic or translational research

Location: Boston University, Bais lab.

 

Excellent opportunities for candidates to learn and apply innovative thinking in target focused research with cutting-edge tools including signaling pathways to translational animal models.  We are interested in candidates having related expertise in one of the 2 areas.

Project 1: Cartilage regeneration, osteoarthritis, tissue regeneration: The goal of this project is to identify cartilage regeneration or protective agents, and biologics for preclinical and clinical application.

Project 2: The goal of the study in NIH funded grant is to evaluate 1) the role of Lysine specific demethylase 1 (LSD1/KDM1A) in squamous cell carcinoma of oral cancer and other cancer types, 2) chemotherapy and immunotherapy combination for future therapeutic applications. The project is in continuation to published studies PMID: 35105672, DOI: 10.1158/1541-7786.MCR-21-0310 and PMID: 29088714, DOI: 10.18632/oncotarget.19637

 

Qualifications:

PhD, DVM or MD in cancer biology, epigenetics, immunology, molecular biology, cell biology, Biotechnology and relevant fields

Required expertise

Project 1 and 2:

• RT-qPCR, Western blot, signaling pathways analysis, lentivirus, Adeno or AAV mediated transduction, CRISPR/Cas9, cell culture, primary cells handling, tissue regeneration, stem cells and immunophenotyping
• Knowledge of proteomics, genomics and single-cell RNAseq analysis are useful but not required.

Project 2:

• Multi-color flow cytometry and histology expertise are preferred
• In vivo mouse handling, tissue dissection, genotyping, histology, and histopathology, Xenograft, orthotopic, and immuno-oncology mouse models
• Good communication skills, enthusiastic and positive team player.
• Strong publication record from previous studies.

 

Please send a resume and letters to bmanish@bu.edu. Available immediately.