Postdoctoral position in the laboratory of Deborah Veis, MD, PhD in the Department of Internal Medicine – Division of Bone and Mineral Diseases, Washington University School of Medicine in St. Louis, MO. The research interest of this lab is to elucidate the cellular and molecular mechanisms underlying pathological bone loss. Major ongoing projects include the study of mitochondrial dynamics in bone cells (osteoblasts and osteoclasts), and mechanisms of host-pathogen interactions in osteomyelitis. The approaches include the use of genetically engineered mice and pathogenic bacterial strains, histological and structural analyses (such as with microCT), confocal microscopy, mechanical testing, and culture of primary murine and human cells.
The applicant must have a PhD degree and should be highly motivated, eager and quick to learn, careful, organized, and reliable. The candidate must be able to work independently and communicate with laboratory staff and collaborating investigators. Strong written and oral communication skills are essential. Expertise in cell culture and molecular biology, mouse genotyping, plasmid and retrovirus preparation and gene transfer, and protein analysis (Western blot, FACS, IHC/IF and ELISA) is helpful. Previous microbiology experience, especially with bacterial culture and genetic manipulation would be a plus, as would experience with whole animal imaging approaches such as bioluminescence imaging or microCT, Experience with histology, including immunostaining and confocal microscopy, and/or with analysis of mitochondria/cell metabolism would be welcome.
To apply for this position, please send a cover letter and C.V. to:
Deborah Veis, MD, PhD