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Our Mission

The Center for Skeletal Research will further the discovery of the causes and therapies for skeletal diseases through the provision of core facilities and other programs designed to make the work of a broad group of investigators more efficient, interdisciplinary, innovative, and interactive. By making this research more effective, advances in understanding and therapy of osteoporosis and other bone disease will occur more quickly.

Research Cores

  • Bone Cells Services

    Bone Cells Services

    We provide high quality skeletally derived osteoblasts, osteoclasts, bone marrow stromal cells and osteocytes, as well as protocols and training for isolating, characterizing and isolating skeletally derived cells. We also develop novel techniques for isolating and studying bone cells.

    Learn More
  • Bone RNAseq Core

    Bone RNAseq Core

    The RNA seq core will provide help and advice with designing of bulk tissue and single cell RNA sequencing experiments, help with tissue and cell preparation, access to space and equipment, expertise for performing bulk RNA extractions from bone and cartilage tissue and computational and statistical interpretation of RNA sequencing data.

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  • Cell Signaling Assay Services

    Cell Signaling Assay Services

    Provides/Enables Assays for Cell Signaling Pathways
    cAMP, IP3, iCa, ERK-1/2, Multi-Array, 1,25 Dihydroxy Vitamin D, 25-Hydroxy Vitamin D, cAMP RIA, CTX-1,FGF-23, Fura-2 iCa++, Glosensor cAMP, IP1, P1NP, p-ERK-1/2, PTH.
    Formats: Luminescence, RIA, ELISA, HTRF
    Kit assays on a per-sample cost-basis.

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  • Histology & Histomorphometry Services

    Histology & Histomorphometry Services

    Close interactions with the Imaging, Bone Cells and Signaling Cores will assure coordinated studies permitting imaging, histology, cell isolation, RNA and signaling analyses on skeletal elements from a single subject.

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  • Imaging and Biomechanical Testing Services

    Imaging and Biomechanical Testing Services

    High-resolution micro-computed tomography (µCT) provides provides non-destructive, quantitative and qualitative assessment of trabecular and cortical bone microarchitecture.

    Learn More

Remember to acknowledge the Center for Skeletal Research (P30 AR066261) if you received funding or services from our cores, see How to Cite P30.


Funded by P30 AR066261.

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Become a Member

The benefits of membership in P30 include subsidized rates in the CSR cores, experienced faculty to assist with projects, networking with other bone scientists, and much more.

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News

  • Fourth Annual Skeletal Research Symposium – June 12, 2018April 2018 - 1:29 pm

    Speakers: Brendan Lee, M.D, PhD, and Dolores Shoback, MD

  • CSR Methods Workshop- Spring 2018February 2018 - 5:00 pm

    CSR Methods Workshop – Spring 2018
    Friday, April 6, 2018; 8:30am-11:45am @ Massachusetts General Hospital.

  • Bone Research Workshop Lecture SeriesJanuary 2018 - 7:00 am

    Friday, April 13, 2018; 3:30pm -5:00pm @ Massachusetts General Hospital Links to: Announcement    Map

  • SPECIMEN DROP OFF/PICK UP IN LONGWOOD AREAJanuary 2018 - 10:20 am

    The CSR is pleased to announce sample drop off and pick up in the Longwood area. Pickups will be scheduled, as needed, on a weekly basis. For more details, see announcement.

Upcoming Events

  1. Bone Research Workshop Lecture Series

    May 11 @ 3:30 pm - 5:00 pm
  2. Vitamin D Workshop

    May 16 - May 19
  3. Bone Research Workshop Lecture Series

    June 8 @ 3:30 pm - 5:00 pm

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Contact us

Center for Skeletal Research
Endocrine Unit
Massachusetts General Hospital
50 Blossom Street, Thier 1101
Boston, MA 02114-2696

Telephone: 617-726-3967
Fax: 617-726-7543
Email: csrmail@partners.org

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